CDSCO Warns Against Painkiller and Antibiotic Misuse
CDSCO has warned against indiscriminate use of painkillers and antibiotics, highlighting risks of kidney damage, adverse reactions and antimicrobial resistance.
The Central Drugs Standard Control Organisation (CDSCO) has issued an advisory warning against the indiscriminate use of painkillers and antibiotics, citing risks including kidney damage, adverse drug reactions and antimicrobial resistance.
In its September 21 circular, the drug regulator said non-steroidal anti-inflammatory drugs (NSAIDs) and antibiotics should be used only when clinically necessary, at the appropriate dose and for the prescribed duration under medical supervision. Most NSAIDs are classified under Schedule H, while most antibiotics fall under Schedule H1 and require a prescription.
The CDSCO warned that repeated or prolonged use of NSAIDs can reduce blood flow to the kidneys and increase the risk of kidney damage and chronic kidney disease. People with existing kidney problems, dehydration or cardiovascular conditions may face greater risks. Doctors have been advised to consider patients’ medical history and other medicines before prescribing these drugs and use the lowest effective dose for the shortest appropriate duration.
The regulator also cautioned against taking antibiotics without medical advice, particularly for viral infections, where they do not work. Unnecessary antibiotic use can contribute to antimicrobial resistance, making bacterial infections more difficult to treat.
Pharmacists and retailers have been directed to follow prescription requirements, while hospitals have been asked to strengthen prescription reviews, patient counselling and antimicrobial stewardship. State drug authorities have also been told to promote awareness and compliance with medicine-sale rules.
